Substrates & reagents for research

MatriMix (511) is a 3D culture substrate developed for cell culture in an in vivo-like environment. By combining collagen, recombinant human laminin-511 E8 fragment, and hyaluronic acid, it provides an extracellular environment suitable for the culture of various types of cells.

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MatriMix for PDX is a substrate for mouse transplantation consisting of collagen, hyaluronic acid, and laminin 511E8, and is designed as a patient-derived xenograft (PDX) model by suspending an equal volume of patient-derived cancer cells mixed in the medium.

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More info for MatriMix series

Brightase-C contains a recombinant collagenase produced by Brevibacillus expression system ^*. It is highly purified, highly stable, endotoxin-free (≤10 EU/mg), and animal-derived components free, and has higher collagenolytic active for cutting type VI collagen than Clostridium histolyticum collagenase.
Since the product doesn’t contain neutral proteinase, we recommend the concomitant use with Brightase-TH for separating cells or separating pancreatic islet.

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*Organism of origin: Grimontia hollisae
Recombinant production in: Brevibacillus chosinensis

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Brightase-TH contains recombinant thermolysin produced by Brevibacillus expression system ^*. It is highly purified, highly stable, endotoxin-free (≤10 EU/mg), and animal derived components free. Since the product doesn’t contain neutral proteinase, we recommend the concomitant use with Brightase-TH for separating cells or separating pancreatic islet.

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*Organism of origin: Bacillus thermoproteolyticus rokko
Recombinant production in: Brevibacillus chosinensis

More info for Brightase series